The Bhais (Term used in India for Underworld Don's) and their goons are back after their mad performances in Welcome (2007). Uday Shetty (Nana Patekar) and Majnu Bhai (Anil Kapoor) have left the underworld, and are now big businessmen. Two women, Chandni (Ankita Shrivastava) and Maharani (Dimple Kapadia), enter their life. Chandni is supposed to be a princess & Maharani a queen, but in reality both are con women and have served jail time in the past. They have been attracted by Uday and Majnu's wealth in Dubai. Chandni is the new love in Uday Shetty and Majnu's life and both friends dream of tying the knot with her. when they realize that they both love the same girl, they decide that whoever has a better Kundli match with Chandni, will get to marry her.However, Appa - Uday's father, makes it challenging by bringing in his other daughter from another marriage, Ranjana (Shruti Haasan). He tells Uday Shetty to get her married to someone from a good family. Maharani also puts a condition that only after their sister is married, will Chandni will marry one of them. Now, a search to find a suitable husband for Ranjana starts. Majnu & Uday reach out to Dr Ghungroo (Paresh Rawal) again to help in the search of a boy from a good family. Dr Ghungroo has just been made aware that his wife had an affair before her marriage to him & has an illicit son from the affair. Dr Ghungroo is on his way to meet him, when he is stopped by Majnu & Uday, who also learn that Ghungroo has a son & decide to marry Ranjana to him. Ghungroo tries to tell them that he has never met his own son, but they don't listen. Ghungroo's son turns out to be the Mumbai don Ajju Barsi (John Abraham). Ghungroo is afraid that Majnu & Uday will kill him if they realize that his son is a Gunda Mawali.But the troubles starts when Ranjana Already has a boyfriend who is the same Ajay "Ajju" Barsi. Ajay turns himself into a nice boy to meet Uday & Majnu, who now go to Ghungroo to call off the marriage with his son. There they realize that Ajay is in fact Ghungroo's son. The wedding is back on, but Majnu suspects that Ajay is not the nice boy he pretends to be. At the engagement party Ajay meets Maharani & Chandani & recognizes then as the con-women from their previous job. At the same party, Majnu gets confirmation from his sources about the truth re: Ajay. He insults Ajay, but Ajay beats up Majnu's goons & declares that he will marry Ranjana, come what may.Now Bhais have to get Ranjana married to a boy with non criminal background by avoiding Ajju and his Temper so that they can get married with the Chandani and while Dr. Ghunghroo has his own Agenda. to downplay Ajju's threat to the wedding Uday & Majnu invite Wanted Bhai (Naseeruddin Shah) to the function. Turns out that Wanted Bhia's son Honey (Shiney Ahuja), is a druggy & is in love with Ranjana, after seeing her once. He wants to marry her at any costs, but doesn't know who she is. Majnu & Uday escape, but find that Wanted & Honey are attending the wedding at Ajju's invite, who has told them that Honey will meet the girl of his dreams at the wedding. At the wedding, Ajju reveals Ranjana to Honey & Wanted Bhai takes the entire party to his private island.Uday is angry and to counter Ajju, he announces his acceptance of Honey's wedding to Ranjana. Ajju instigates Chandani to have an affair with Honey. Maharani agrees as she feels Wanted Bhai is a bigger party than Majnu & Uday. Ajju then also plants a thought in Honey's mind that he actually loves Chandani & Honey believes him. Uday & Majnu are depressed & drive away. Ranjana believes that they are driving away to suicide. She surrenders & says that she will not wed against their wishes. Ajju also backs away from Ranjana for her happiness. Majnu & Uday realize that they truly love each other, & give them their blessings.In a twist, Wanted Bhai reveals that he has been keeping an eye on everyone through cameras on his island. He knows the angle of each and every person. As their game gets exposed, everyone captures Honey & runs towards the desert. Wanted Bhai follows, where Ajju saves his life from a herd of approaching camels. Wanted Bhai adopts Ajju & agrees to get him married to Ranjana.