NOTE: Sequel to John Carpenter's Vampires (1998).Los Muertos picks up after the vampires went south into Mexico and Father Guiteau stashed the Bersier cross in a monastery. Vampire hunter Derek Bliss [Jon Bon Jovi] has been commissioned to seek and destroy some vampires in northern Mexico before they can move north to San Diego and other places in the U.S. The only problem is that the unnamed client wants to hire a team, not someone working solo. Getting together a team is a bit difficult for Derek because everyone on Chief Brody's recommended list keeps turning up dead. Father Guiteau, who was a member of the original team lead by Jack Crow, died last month. All the priests at the monastery where he moved the Bersier cross were killed by vampires only a day or two after Derek came looking for Guiteau.Eventually, Derek manages to put together a team, unlikely as it is. It consists of Zoey [Natasha Wagner] (a woman he met in a diner who was bitten by a vampire but who has been able to keep the turning in remission by taking some anti-HIV pills she got in Mexico City), Father Rodrigo[Cristian de la Fuente] (the only priest who escaped the massacre at the monastery), Sancho [Diego Luna] (a 15-year old boy who accompanied Derek on a vampire hunt and who found that he had a penchant for it), and Ray Collins [Darius McCrary] (a tall, muscular, black, ex-military, "tough as nails" guy recruited in Memphis by Brody). To help with the hunt, Rodrigo offers Derek the use of Guiteau's vampire-hunting bus, which is outfitted with all the winches and gizmos that are needed to hunt vampires (or "suckers," as the team calls them).The attack on the monastery, Rodrigo explains, was led by the new female master Una [Arly Jover] in order to get back the Bersier cross. It looks like she intends to again perform the ritual which the suckers believe will allow them to walk during the day. After meeting up with Collins in Nogales, they cross over into Mexico. Zoey, due to her blood connection with the vampires, has a vision of Una performing the ceremony, but it doesn't seem to have worked. The sun still hurts her. Given a map of Mexico, Zoey is able to pinpoint where she thinks the bloodsuckers are hiding...someplace called Salina, near some old Toltec ruins. They stop for the night to sleep, but Collins is getting claustrophobic in the little bus and chooses to sleep outside. During the night, he is, unknown to anyone, bitten by Una. The next day is spent driving further into Mexico. They know that they are getting close when they stop for gas and cold drinks and find that everyone in the diner has been slaughtered.The next morning, they near Salina. Rather than going directly to the ruins, they stop in Salina where the residents are celebrating the Day of the Dead ("Los muertos" means "the dead"). When Zoey goes to take her meds, she finds them missing and says that she must go immediately to Mexico City. Actually, Una has them, and she's downed every last one. This gives Una the ability, albeit it temporary, to move about during daylight, and she uses that opportunity to find and kidnap Zoey. Rodrigo puts 2+2 together and concludes that Una took Zoey's meds. But the only ones who had access to them were the rest of the team, so Derek holds them all at gunpoint, trying to find the culprit. Turns out that it was Collins, who is shot by an old man they just met that morning in Salina. With his dying breath, Collins reveals that the client who hired them is none other than Una.Although they now know that this entire vampire hunt is a set-up, the remaining team members plus the old man, filling in for Collins, go to the ruins to rescue Zoey. Zoey has fallen into a deep shaft and needs to be lifted out. Derek tosses her a rope, telling the old man to stay far enough behind him to watch his back while still keeping his eye on Rodrigo and Sancho, who are closer to the exit. While they are so separated, Una attacks Derek. Just as she's about to bite his neck, Fr Rodrigo offers Una a deal. Let his friends go, and he'll offer himself, as a priest, to perform the ceremony. In addition, he points out, he is also a hunter--two of the necessary elements of the ritual. Una agrees.Rodrigo stays with Una while the others go to a clinic where Zoey is transfused with blood while her infected blood is removed in hopes that this will slow her turning. Then Derek gets a brainstorm. He asks the nurse to transfuse Zoey's tainted blood into him so that he can slow his heartbeat and infiltrate the vampires without being noticed. As the sun sets, the team goes back to the ruins where the ritual is taking place. Una has slit Rodrigo's leg and drunk a cup of his blood when Rodrigo mentions that the ritual won't work because he was merely a hired hand at the monastery, not a priest at all. Ha ha, fooled you! Derek, whose plan to lurk is working, shoots several suckers, saves Rodrigo from being burned alive, and fires an arrow through Una. Unfortunately, the winch is on the fritz, and they can't pull her out into the sun.So, they fix the winch and go back into the ruins. Sancho ropes Una, Una grabs Derek, Zoey pulls both Una and Derek out into the sun, Derek shoots off Una's head, and Una burns up. [I wonder whether they'll get paid now that they've killed their client?]Epilogue: Rodrigo stays in Salina, Sancho is sent home to his mother, and Derek and Zoey drive off together into the sunset, headed for Mexico City, as they are both in need of those meds. [Original synopsis by bj_kuehl]