A touching comic story of two women, who truly test the meaning of the phrase "best friends." Coming from disparate worlds, these two friends bond through a chance meeting followed by a series of unpredictable events. Together, Ellen (Gina McKee) and Cora (Helena Bonham Carter) help each other with all that life throws at them - lovers, divorce, children, debts and too much vodka. A colorful and quirky set of friends (James Nesbitt, Richard Wilson) share in their ups and downs, and force the pair to unravel a dark secret that they unknowingly share.