In New York, four men have their penis ripped in room 308 of the cheap Hotel Quickie. The Sicilian homosexual smoker Detective Luigi Mackeroni is in charge of the investigation. While inquiring in the hotel, Mackeroni has a crush on the prostitute Billy, goes with Billy to room 308 and they have intercourse in the crime scene. Luigi uses the condom supplied as compliment by the hotel and it eats his testicle. The official version for the police department is that Billy torn Mackeroni's testicle, and nobody believes in Mackeroni's version. After many other mutilations, Mackeroni finds that a fanatic religious woman intends to destroy gays, hookers, travesties and other perverts, using this weird specimen developed in the laboratory to castrate men.—Claudio Carvalho, Rio de Janeiro, Brazil