Two dangerous outlaws known as the Gecko brothers (Clooney, Tarantino) kidnap a family and head south to a seedy Mexican bar to hide out in safety. Before long it becomes apparent that the place they've entered is not your average bar; the entire place is teeming with vicious, blood-sucking vampires. With the odds stacked against them, the Gecko brothers are forced to team up with their hostages if they stand any chance of getting out alive.