The brilliant Eddie Jessup has PhD in medicine and is conducting experiments with students with an isolation chamber. He decides to be the subject of his experiments with the support of his colleague and friend Mason Parrish and has religious visions. Then he goes to a party, where he meets Emily, who falls in love with him and asks him to marry her. Seven years later, they are married with children and both work in Harvard Medical School. Eddie believes he is too conventional and respectful in Harvard, and decides to travel to Mexico to meets Prof. Eccheverria and participate in an Indian ritual with mushrooms and other hallucinogens. When he returns home, he brings the drug and uses an isolation chamber to increase its effects under the supervision of Mason and Arthur Rosenberg. But soon he becomes uncontrollable and Emily, Mason and Arthur fear for his fate.—Claudio Carvalho, Rio de Janeiro, Brazil